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Valacyclovir is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. Valacyclovir tablets may be given without regard to meals. Valacyclovir oral suspension (25 mg/mL or 50 mg/mL) may be prepared extemporaneously from the 500-mg valacyclovir tablets for use in ... Valaciclovir is a prodrug that is converted to aciclovir in the body and used to treat and prevent infections caused by herpes simplex, herpes zoster and cytomegalovirus. It is taken by mouth and has common side effects such as headache and vomiting, and may cause kidney problems in some cases. Find patient medical information for Valacyclovir (Valtrex) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings