Learn about the inductive effect in organic chemistry, a local change in electron density due to electron-withdrawing or electron-donating groups. Find out how it affects bond polarization, acidity, basicity, and fragmentation of molecules. The inductive effect and resonance both relate to the distribution of electrons in a chemical bond, but are two different and distinct effects . Electronic factors that influence organic reactions include the inductive effect, electromeric effect, resonance effects, and hyperconjugation . These electronic factors involve organic molecules, most of which are made from a combination of the following six elements: carbon, hydrogen, nitrogen, oxygen, phosphorus, and sulfur (known collectively as CHNOPS). Yet, the limited number of building blocks does not prevent organic compounds from taking on diverse properties in their physical ... Negative inductive effect (-I effect ): Due to electron-withdrawing nature of the group, electron density decreases. Thus, basic nature is decreased and acidic nature is increased.
