Define doctrine. doctrine synonyms, doctrine pronunciation, doctrine translation, English dictionary definition of doctrine. n. 1. A principle or body of principles presented for acceptance or belief, as by a religious, political, scientific, or philosophic group; dogma. 2. What does doctrine mean? Learn the meaning of doctrine and its definition. Understand what doctrine means, get detailed explanations, usage examples, and discover the meaning of doctrine in different contexts. Definition of doctrine noun from the Oxford Advanced Learner's Dictionary. [countable, uncountable] a belief or set of beliefs held and taught by a Church, a political party, etc. He challenged the Christian doctrine of Original Sin. He was deeply committed to political doctrines of social equality. Definition of Doctrine in the Definitions.net dictionary. Meaning of Doctrine. What does Doctrine mean? Information and translations of Doctrine in the most comprehensive dictionary definitions resource on the web.