coagulation, in physiology, the process by which a blood clot is formed . The formation of a clot is often referred to as secondary hemostasis, because it forms the second stage in the process of arresting the loss of blood from a ruptured vessel. COAGULATION definition: 1. the process by which blood changes into a solid state to form a solid seal 2. the process by…. Learn more. “Platelets are minute fragments of blood cells that help in the formation of clots in the body to stop bleeding.” Any damage in the blood vessels sends signals to the platelets. The platelets rush to the site of damage and form clots to repair the damage. The activated platelets stick together to form a platelet plug which in turn activates the coagulation factor. Vitamin K is beneficial for the proper functioning of the coagulation factor. Let us have an overview of platelets and ... coagulation factors factors essential to normal blood clotting, whose absence, diminution, or excess may lead to abnormality of the clotting. Twelve factors, commonly designated by Roman numerals, have been described (I–V and VII–XIII; VI is no longer considered to have a clotting function). (See table 6.) Factor I is a high-molecular-weight plasma protein that is converted to fibrin through the action of thrombin; deficiency conditions are called afibrinogenemia and hypofibrinogenemia ...

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