Xylazine , or 'tranq,' is a new lethal drug on the streets. Understand its effects, potential risks, and the impact of this tranquilizer on mental health. Xylazine is a structural analog of clonidine and an α 2 -adrenergic receptor agonist, [1] sold under many trade names worldwide, most notably the Bayer brand name Rompun, [2] as well as Anased, Sedazine and Chanazine. [3] Xylazine is a common veterinary drug used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle, and other mammals. [2] In veterinary anesthesia, it is often used in combination with ketamine. Veterinarians also use xylazine as an ... Xylazine is a drug used in veterinary medicine to sedate, relieve pain, and induce muscle relaxation in animals. It is also a common adulterant in illicit drug combinations, especially those containing opioids. Xylazine is a non-opioid and clonidine analog with analgesic and muscle relaxant properties used as a tranquilizer used in veterinary medicine.