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White Spots on Face: Types, Causes and How to Treat them Discover what those white patches really mean — from common conditions like vitiligo and fungal infections to simple skin imbalances — and learn safe, effective ways to restore your skin ’s even tone. White spots often form due to loss of melanin—the pigment that colors skin —or from superficial skin debris like dead cells. Depending on the cause, they may appear as small dots or larger patches. Causes of white spots on your skin can include sun exposure, milia, or vitiligo. See all the possible causes and potential treatments.