Definition: Spermatogenesis is the process of sperm cell formation that takes place in the seminiferous tubules of the testes. It includes stages like multiplication, growth, maturation, spermiogenesis, and spermiation. Describe the stages of spermatogenesis in the seminiferous tubule, including the roles of the nurse (sustentacular, Sertoli) cells and interstitial cells (of Leydig). The process of spermatogenesis , i.e., the formation of sperms, is an essential part of reproduction in humans and all kinds of animals. In this article, we will learn about where and when spermatogenesis occurs, and what are the stages that the cells need to go through to complete the process. Spermatogenesis is the biological process of producing sperm cells . It occurs in the male gonad of a sexually reproducing organism. In this process, the undifferentiated male germ cells develop into spermatozoa through a series of events.