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Most people are either born with a deviated septum or get it as a result of an injury, but there are multiple other causes. Learn more. A deviated septum happens when the thin wall between the nasal passages, called the nasal septum , is off to one side. The nasal septum being off-center, called deviated, makes one side of the inside of the nose smaller. A deviated septum can block one side of the nose. The reduced airflow can make it hard to breathe. A deviated septum also can lead to a nose that looks crooked in some people. Medicines might reduce the swelling inside the nose. Surgery is needed to correct a deviated septum . Explore the role of the septum in human anatomy, its different types, and its significance in various bodily functions. A septum is a wall that divides a cavity or structure into smaller ones. Learn about the septa in human anatomy, cell biology, botany, zoology and laboratory technology.