Detailed Mirabegron dosage information for adults and children. Includes dosages for Urinary Frequency, Urinary Incontinence, Bladder Muscle Dysfunction - Overactive and more; plus renal, liver and dialysis adjustments. Mirabegron is a beta 3-receptor agonist. It works by activating the receptor in the bladder, causing the bladder muscles to relax. It prevents frequent, urgent or uncontrolled urination. Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Coadministration of digoxin 0.25 mg with a combination of solifenacin 5 mg and mirabegron 50 mg increased digoxin AUC and peak plasma concentration by ~10% and 14%, respectively Miragron 25mg Tablet ER helps to treat uncontrollable contractions (spasms) of the bladder muscles that cause frequent urination, urgent need to urinate, and inability to control the passing of urine. It also relieves painful, or frequent urination and reduces the urgency to urinate that may occur with some infections of the urinary tract. This way it helps manage the overactive bladder symptoms efficiently.