Isolation means completely alone, like the stranded skiers who were in total isolation after an avalanche stranded them at the top of a mountain. Isolation meanings, definitions, synonyms, and antonym. Explore more Negative Words at Dictionary by BUHAVE. (2025) BUHAVE Isolation is the state of feeling alone and without friends or help, or the act of separating something from others. Learn more about the different meanings, synonyms, examples, and usage of isolation in various contexts. Definition of isolation noun in Oxford Advanced American Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.

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