Vistaril ( hydroxyzine ) is used as a sedative to treat anxiety and tension and to treat allergic skin reactions. Includes Vistaril side effects. interactions and indications. Learn about the side effects of hydroxyzine , from common to rare, for consumers and healthcare professionals. Hydroxyzine package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology. Hydroxyzine Interactions There are 585 drugs known to interact with hydroxyzine , along with 9 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 95 are major, 486 are moderate, and 4 are minor.

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