Human metapneumovirus life cycle: Footnote

Footnote: Schematic representation of the human metapneumovirus life cycle. After attachment of the virion to the plasma membrane, the viral and plasma membranes fuse, resulting in uncoating of the virion and release of the RNP (containing the negative-sense viral RNA) into the cytoplasm. After primary transcription, the genome is replicated to produce the antigenome. The antigenome is used to synthesize genomic RNA, which is used to produce additional antigenomes for incorporation into ... In this review, we highlight recent advancements in treatment, adult infections, and the structural features of known antigenic sites on the HMPV proteins. Etiology, Treatment, Acute Respiratory Infection, Clinical Characteristics, Epidemiology, Human Metapneumovirus (HMPV) Human metapneumovirus (hMPV) is a respiratory virus, first reported the year 2001. Since then, it has been described as one of the main etiological agents that causes acute lower respiratory tract infections (ALRTIs), which is characterized by symptoms such as bronchiolitis, wheezing and coughing. Most people get HMPV before they turn 5. You can get HMPV again, but symptoms are usually mild after your first infection. Is human metapneumovirus just a cold? Human metapneumovirus most often causes symptoms similar to a cold, but some people can get very sick.