Discover the biblical meaning of consecrate and its significance in spiritual life. Enhance your relationship with God through dedication. The meaning of CONSECRATE is dedicated to a sacred purpose. How to use consecrate in a sentence. Synonym Discussion of Consecrate. consecration (to something) the act of giving something/somebody/yourself to a special purpose, especially a religious one. As a sign of their consecration to religious life, they are to clothe themselves plainly and to live in simplicity. Definition of consecration noun in Oxford Advanced Learner's Dictionary. Consecration definition: the act of consecrating; dedication to the service and worship of a deity.. See examples of CONSECRATION used in a sentence.