Cilostazol is a phosphodiesterase 3 inhibitor that helps improve symptoms of peripheral vascular disease and prevents stroke. It is taken by mouth and may cause side effects such as headache, diarrhea, and low blood cells. Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand name Pletal by Otsuka Pharmaceutical Co.. Cilostazol is an allopathic medicine The correct dosage of Cilostazol depends on the patient's age, gender, and medical history. This information has been provided in detail in the dosage section. Cilostazol tablets are contraindicated in patients with heart failure of any severity. Cilostazol and several of its metabolites are inhibitors of phosphodiesterase III. Several drugs with this pharmacologic effect have caused decreased survival compared to placebo in patients with class III-IV heart failure [see Contraindications (4)]. Close
