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Chymotrypsin is a digestive enzyme belonging to a super family of enzymes called serine proteases. It uses an active serine residue to perform hydrolysis on the C-terminus of the aromatic amino acids of other proteins. Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Trypsin enzymes help you digest proteins. A lack of it is connected to cystic fibrosis, pancreatitis, and malabsorption. Supplements are sometimes used to ease digestion, heal wounds, and more. Learn if it can really help with these and other issues. Chymotrypsin is an enzyme that breaks down proteins and is used to make medicine for various conditions. Learn about its effectiveness, safety, dosage, and interactions from WebMD.