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Ceramide is composed of sphingosine and a fatty acid joined by an amide bond. It is involved in various cellular signaling, such as apoptosis, differentiation, and inflammation, and can be synthesized or degraded by different pathways. Ceramides are lipids, or fatty molecules, that help maintain a healthy skin barrier. They’re a common ingredient in skin-care products including moisturizers and safe for all skin types ... Moisturizers, creams, cleansers and other skin care products containing ceramides can help repair the skin’s barrier and relieve dryness. Since external factors (harsh weather, over-exfoliation) can deplete ceramides, replenishing them is key to maintaining healthy, resilient skin and hair.