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Calamine is used in the treatment of Dermatitis, Itching, Eczema. View Calamine ’s uses, side-effects, drug interactions, expert advice and user FAQs only on 1mg.com. Calamine is a topical lotion or cream made from zinc oxide and ferric oxide. It is used to treat mild skin conditions such as sunburn, insect bites, or poison ivy. Uncover the benefits of calamine lotion and why this pink lotion is a year-round skincare essential! Learn how to use it for soothing rashes, allergies, sunburns and more.