Acute renal failure: Acute kidney injury happens

Acute kidney injury happens when the kidneys suddenly can't filter waste products from the blood. When the kidneys can't filter wastes, harmful levels of wastes may build up. The blood's chemical makeup may get out of balance. Acute kidney injury used to be called acute kidney failure . Acute kidney injury (AKI) is a clinical syndrome manifested by a rapid or abrupt decline in kidney function and subsequent dysregulation of the body electrolytes and volume, and abnormal retention of nitrogenous waste. AKI was formerly known as acute renal failure . AKI is a complex condition with a wide range of causes, including ischemic injury and exposure to nephrotoxic agents. [1] The widely accepted Kidney Disease : Improving Global Outcome (KDIGO) definition of AKI is based on the ... In this review, the epidemiology and pathophysiology of ARF are discussed, including the vascular, tubular, and inflammatory perturbations. The clinical evaluation of ARF and implications for potential future therapies to decrease the high mortality are described. Acute kidney failure ( acute kidney injury) happens when your kidneys suddenly stop functioning and cannot filter waste and toxins from your blood.