Scrub Typhus - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version. Scrub typhus , also known as bush typhus, is a disease caused by bacteria called Orientia tsutsugamushi. You can get it if an infected chigger – larvae that grow into mites – bites you. Chiggers... Scrub typhus , an acute febrile illness caused by Orientia tsutsugamushi, is an underdiagnosed but re-emerging vector-borne zoonosis in India. The disease is endemic in several Indian states and is characterised by non-specific symptoms, often leading to diagnostic delays and high mortality in untreated cases. This comprehensive article delves into its pathophysiology, clinical manifestations, epidemiological trends, diagnostic challenges, and current treatment strategies. Scrub typhus is a form of typhus caused by a parasite transmitted by mites in areas of scrub vegetation. It can cause fever, rash, cough, and complications such as encephalitis and myocarditis. Learn how to diagnose and treat it with antibiotics or other drugs.