Lamictal is a generic drug used to treat certain types of seizures and bipolar disorder. Learn about its side effects, dosage, interactions, warnings, and how to avoid serious skin rashes. Lamotrigine is an anti-epileptic medication used for seizures in adults and children over 2 years old and bipolar disorder (manic depression). Learn about side effects, interactions, and indications. NHS medicines information on lamotrigine – what it's used for, side effects, dosage and who can take it. Lamotrigine likely acts by inhibiting sodium currents by selective binding to the inactive sodium channel, suppressing the release of the excitatory amino acid, glutamate. The mechanism of action of lamotrigine in reducing anticonvulsant activity is likely the same in managing bipolar disorder.
