Learn the 10 early signs of kidney problems to watch for, including fatigue, foamy urine, swelling, and more. Early detection is key to preventing kidney disease progression. Warning signs and symptoms of kidney disease If your kidney function continues to decline, you may start developing symptoms of kidney disease . Each person is different, but most people will start to develop uremia as the kidneys fail and are unable to remove wastes from the body. Signs and symptoms of kidney disease may include foamy urine, fatigue, and swelling. Most people are unaware of the disease in its early stages.
