An isotonic solution is one that has the same solute concentration and osmotic pressure as the cell. Learn how it affects the cell size and shape, and see examples of isotonic solutions in animals, blood and plants. The difference between isosmotic and isotonic solution is their concentration. An isosmotic solution refers to two solutions that have the same total solute concentration, but an isotonic solution refers specifically to a solution that has the same solute concentration as a particular cell or tissue. Types of solutions according to tonicity Isotonic solutions cause no swelling or contraction of the tissues with which they come in contact and produce no discomfort when instilled in the eye, nasal tract, and blood such as isotonic sodium chloride. In an isotonic solution, the concentration of solutes inside and outside the cell is balanced , resulting in no net movement of water across the membrane. Isotonic solutions help prevent excessive water gain or loss in cells, ensuring their proper functioning.