ISC is a qualification awarded to students after completing the twelfth grade in India. It is conducted by the CISCE and has three streams: Science, Commerce, and Arts. Learn more about the structure, assessment, and importance of ISC . The full form of ISC is Indian School Certificate. It refers to the higher secondary or 12th class exam conducted by CISCE (Council for Indian School Certificate Examinations). ISC full form is Indian School Certificate, an examination conducted by CISCE for Class 12 students, recognized nationally and internationally. Full form of ISC What is the full form of ISC ? The full form of ISC is Indian School Certificate, which is the certificate that is awarded to students from schools that are affiliated to the Council for the Indian School Certificate Examination (CISCE) after passing their class 12th Examinations.