4 meanings: 1. a forceful expression of dismissal or contempt 2. to go away 3. to irritate or annoy (a person) 4. very large or.... Click for more definitions. fuck off definition : leave or go away, used in anger or annoyance. Check meanings, examples, usage tips, pronunciation, domains, related words. FUCK OFF meaning : 1. to leave or go away, used especially as a rude way of telling someone to go away 2. a rude…. Learn more. fuck off (third-person singular simple present fucks off , present participle fucking off , simple past and past participle fucked off ) (vulgar) (intransitive, idiomatic) To go to hell; to disappear or go away; to screw oneself. quotations