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Explore the 5 key differences between DNA and RNA , including function, structure and location, with examples and insights from modern molecular biology. RNA uses DNA to code for the structure of proteins synthesized in cells, and it is also the genetic material of certain viruses. There are several chemical differences between the two structures. As the name deoxyribonucleic acid suggests, DNA has a sugar known as deoxyribose in the “backbone” of the molecule. Discover the key differences between DNA and RNA , their structures, functions, and unique roles in genetic coding and protein synthesis. In the above table, the basic difference between DNA and RNA is covered on the basis of their structure and function. Interesting Facts on DNA and RNA DNA was first discovered and identified by the Swiss biologist Johannes Friedrich Miescher in 1869. He found DNA while experimenting with blood cells. James Watson and Francis Crick later discovered the double helix structure of a DNA molecule. They proved that DNA is responsible for storing genetic information in living organisms. The most ...