Learn about the diagnosis and treatment of De Quervain ' s Tenosynovitis , a stenosing tenosynovial inflammation of the 1st dorsal compartment of the wrist. Find out the epidemiology, anatomy, pathophysiology, presentation, imaging, differential diagnosis, and surgical techniques of this condition. Learn about de Quervain ’ s tenosynovitis , a painful condition that affects your thumb tendons and wrist. Find out the causes, diagnosis, treatment options and prevention tips from Cleveland Clinic experts. Learn about the causes, symptoms, diagnosis and treatment of De Quervain ' s tenosynovitis , a condition that affects the tendons of the thumb side of the wrist. Find out how to prevent, manage and recover from this painful disorder with nonsurgical or surgical options. De Quervain tenosynovitis is pain and swelling in the tendons around your thumb, the abductor pollicis longus and extensor pollicis brevis.