Early signs of bone cancer include pain, swelling, and unexplained fatigue or weight loss. Bone cancers include several types of rare, malignant tumors that start in your bones. Learn more about the types and treatments. Bone cancer destroys normal bone tissue. Learn more about the symptoms , risk factors, diagnosis, types, treatment, and outlook for bone cancer . Learn to recognize the 12 early signs of bone cancer . From persistent pain to swelling, discover when to seek help and why early detection is crucial.