Learn how the body prevents excessive bleeding when a blood vessel is injured. Find out the roles of platelets, clotting factors, and fibrin in the blood clotting process and its disorders. Coagulation , in physiology, the process by which a blood clot is formed. The formation of a clot is often referred to as secondary hemostasis, because it forms the second stage in the process of arresting the loss of blood from a ruptured vessel. ( Blood vessel constriction and platelet aggregation is the first stage.) Learn about the process of blood coagulation or clotting , the factors involved, the pathways and the disorders. Find out how platelets, fibrin and clotting factors work together to prevent bleeding and form a clot. Blood coagulation , also known as clotting , is the body's natural defence mechanism to prevent excessive bleeding. It is a complex process where liquid blood transforms into a gel-like mass, forming a clot at the site of an injury to a blood vessel. This seals the wound, allows for healing, and stops blood loss.
