A small saclike organ located at the upper end of the large intestine . The appendix has no known function in present-day humans, but it may have played a role in the digestive system in humans of earlier times. The appendix is also called the vermiform appendix because of its wormlike (“vermiform”) shape. The meaning of appendix . Definition of appendix . English dictionary and integrated thesaurus for learners, writers, teachers, and students with advanced, intermediate, and beginner levels. The meaning of APPENDIX is appendage. How to use appendix in a sentence. The appendix is a finger-like tube in the lower right part of the abdomen. Its role has long been a mystery, but some experts believe they’re closer to understanding its function.