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Aceclofenac is an oral non-steroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties used to treat osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). This drug is mainly used as a pain reliever for various conditions in the body. commonly prescribed for conditions such as rheumatoid arthritis. Aceclofenac is a NSAID used to treat fever and inflammation in arthritis and spondylitis. Learn about its brand names, contraindications, warnings, and how to take it safely.